CN106999355A, EP3177273A1, WO2016012452A1
Inventors: J. M. Delgado Lopez, J. Gomez Morales, R. Fernandez Penas, M. Iafisco, A. Tampieri, S. Panseri
Owner: Consiglio Nazionale delle Ricerche (50%); Consejo Superior De Investigaciones Científicas (C SIC) (50%)
Description
Process for obtaining fluoride-doped citrate-coated amorphous calcium phosphate nanoparticles. This material has applications in biomedicine due to its biodegradability and bioactivity; it also promotes cell adhesion and osteogeneration. In dentistry, it may be used in toothpastes, mouthwashes, chewing gums, gels and fluoride varnishes as a remineralising agent of dentine and enamel. The process to generate these particles is eco-efficient and eco-friendly, as it does not leave any acid residue; it consists of a single stage and it is the first time that an amorphous calcium phosphate coated with citrate and doped with fluoride, which enhances its remineralising action, is obtained.
Contact: Michele Iafisco